Chronic pain such as pain resulting from nerve damage is associated with neuro-inflammation, in both peripheral and central nervous system (CNS). Indeed, peripheral immune cells such as macrophages and CNS microglia are involved in pain pathophysiology. Current research predominately focuses on the contribution of these cells to pain pathogenesis. The main objective of this project is to examine pain-inhibiting actions of macrophages and microglia in the peripheral and central nervous system.
Group members involved: Halina Machelska, M. Özgür Celik, Dominika Labuz